Mathematical
Diseases-theraReCliNostic-Research Institute
Shaping a Better Health One Equation at a Time
Welcome to MDtRI, where interdisciplinary research meets mathematical modeling to address global health challenges.
Welcome to MDtRI, where interdisciplinary research meets mathematical modeling to address global health challenges.
Innovative Research
At MDtRI, we are committed to exploring new concepts and ideas to improve human health. Our research is highly collaborative. Learn more about our work below.
RiVela (Riemann inspiration Visualization
& enriched clusters lanscape)
Harshita Sinha, "No child chooses the mutations they're born with, yet those mutations can determine everything. I wanted to be part of the solution, especially when they can be fatal. That drive led me to develop an independent research project on Group 3 Medulloblastoma, working toward something that could one day help real patients.
That fight also led me somewhere I'm incredibly proud of: placing 4th at the Washington HOSA State Research Poster competition and earning recognition from the Ben Towne Center at Seattle Children's Research Institute at the Central Sound Region Science and Engineering Fair. Moments I'll never forget. However, I didn't get there alone. Dr. Lokendra Thakur at MDtRI gave me more than guidance, his mentorship shaped me into a more determined researcher, and being part of the MDtRI team has been a true privilege. Ms. Cullison at Lake Stevens High School who never stopped believing in me, even when I doubted myself. And my parents, my foundation through every setback and breakthrough, made all of it possible. This recognition belongs to all of them. I'm just grateful I get to keep going."
Updates
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Our abstract submission has been accepted for a poster presentation at AAIC 2026, London, UK.
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Congratulations to our higher school researcher, Harshita Sinha, for (i) winning the prestigious Seattle Children's Research Institute Cancer and Blood Cancer Award and (ii) securing 4th place in the Washington state-level competition.
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Our Letter Of Intent is invited to submit a full Proposal for Phase II of the Nuttall Women’s Health grant process.
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Our iEL team lead and PI, was invited by an AAIC 2026 Scientific Program Committee to serve as an Abstract Reviewer (2026).
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Our Letter Of Intent application for the Alzheimer's Association Research Grant For All (AARGA) is approved.
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Publications: we have successfully published five preprints (Dg-Dig-SSNs (AMR diagnostics), Sheaf-ML, ci-fGBD, Microbeyt, and MAP-PRS).
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Successfully launched the Biomedical Research Training & Skills Development Program (BRT&SDP) to foster next-generation scientific talent.
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Participated at the Alzheimer’s Association International Conference (AAIC) in Toronto, Canada.
Biomedical Research Training & Skills Development Program
Unlock Your Potential in Biomedical Research!
Gain hands-on training, expert mentorship, and real-world experience to build skills, critical thinking, and confidence.
Apply now! Selection is by the Training & Skills Development Committee, and no fees apply for selected candidates.
Note: Applications are reviewed on a rolling basis in three-month cycles (Jan–Mar, Apr–Jun, Jul–Sep, Oct–Dec).
Bridging Education
&
Biomedical Research
Excellence
Bushra Malik
University of Toronto, Canada
👉 "During my training at MDtRI, I gained hands-on experience in advanced computational biology, data integration, and research methodology. I not only learned how to apply innovative clustering and analytical techniques to complex, multimodal datasets, but also developed critical skills in problem-solving, collaboration, and scientific communication. This training provided me with the foundation and confidence to transition into the MDtRI research team, where I was able to contribute meaningfully to projects at the intersection of mathematics, computation, and biomedical science— leading to a published research paper. The program did a great job in helping transform my academic knowledge into practical expertise!"
Harshita Sinha
Seatle, Washington, USA
👉 “This training program taught me that 80% of research is developing the right question and planning how to interpret data, while experimentation comes last.
Through the 4-week training, I gained vital skills in breaking down the research process and choosing the right data for each project.
I’m grateful to join the MDtRI research team and collaborate with high-level researchers.”
Funding:
Collaboration:
